74628-13-0Relevant articles and documents
A convenient synthesis of unsymmetrical, substituted γ-pyrones from Meldrum's acid
Zawacki, Frank J.,Crimmins, Michael T.
, p. 6499 - 6502 (1996)
A unique approach to the synthesis of mono and disubstituted γ-pyrones from acylated Meldrum's acid and vinyl ethers has been developed. The convenient one pot synthesis of these versatile polyketide equivalents is accomplished without strong base or low temperature.
A CONVENIENT SYNTHESIS OF SUBSTITUTED γ-PYRONES
Koreeda, Masato,Akagi, Hiroshi
, p. 1197 - 1200 (2007/10/02)
An efficient and general synthetic method for various 2-mono- and 2,6-disubstituted γ-pyrones has been developed.This utilizes the C-acylation (70-85percent) of β-methoxy-α,β-enone lithium enolates 4 by acid chlorides 3 followed by the acid-catalyzed cycl