746599-28-0Relevant academic research and scientific papers
Discovery of substituted 4-anilino-2-arylpyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. 2. Structure-activity relationships of the 2-aryl group
Sirisoma, Nilantha,Pervin, Azra,Nguyen, Bao,Crogan-Grundy, Candace,Kasibhatla, Shailaja,Tseng, Ben,Drewe, John,Cai, Sui Xiong
, p. 2305 - 2309 (2009)
As a continuation of our efforts to discover and develop the apoptosis inducing 4-anilino-2-(2-pyridyl)pyrimidines as potential anticancer agents, we explored replacing the 2-pyridyl group by other aryl groups. SAR studies showed that the 2-pyridyl group
