746624-40-8Relevant academic research and scientific papers
Racemic and chiral sulfoxides as potential prodrugs of 4-pyrone COX-2 inhibitors
Caturla, Francisco,Amat, Merce,Reinoso, Raquel F.,Calaf, Elena,Warrellow, Graham
, p. 3605 - 3608 (2007/10/03)
The preparation of the sulfoxide analogues 7, 8, and 9 and their enantiomerically pure forms is discussed as well as their ability to act as prodrugs of the potent and selective sulfone-containing COX-2 inhibitors 1, 2, and 3. Sulfoxide derivatives 7 and
2-PHENYLPYRAN-4-ONE DERIVATIVES AS SELECTIVE COX-2 INHIBITORS
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Page 14, (2008/06/13)
The present invention relates to 2-phenylpyran-4-derivatives of general formula (I) processes for their preparation, pharmaceutical compositions containing them, and their medical uses.
