746624-41-9

Upstream product

• 108-24-7 acetic anhydride 
• 708276-51-1 2-(4-chloro-2-fluorophenoxy)-1-(4-methylsulfanylphenyl)ethanone 

Relevant academic research and scientific papers

Racemic and chiral sulfoxides as potential prodrugs of 4-pyrone COX-2 inhibitors

The preparation of the sulfoxide analogues 7, 8, and 9 and their enantiomerically pure forms is discussed as well as their ability to act as prodrugs of the potent and selective sulfone-containing COX-2 inhibitors 1, 2, and 3. Sulfoxide derivatives 7 and

2-PHENYLPYRAN-4-ONE DERIVATIVES AS SELECTIVE COX-2 INHIBITORS

The present invention relates to 2-phenylpyran-4-derivatives of general formula (I) processes for their preparation, pharmaceutical compositions containing them, and their medical uses.