74663-96-0

Basic information

• Product Name: 3-METHYL-4-PYRIDINECARBOXALDEHYDE
• Synonyms: ASINEX-REAG BAS 07731954;3-METHYL-PYRIDINE-4-CARBALDEHYDE;3-METHYLPYRIDINE-4-CARBOXALDEHYDE;3-METHYL-4-PYRIDINECARBOXALDEHYDE;4-Pyridinecarboxaldehyde, 3-methyl- (9CI);3-Methylisonicotinaldehyde;3-METHYL-4-PYRIDINEC
• CAS NO: 74663-96-0
• Molecular Formula: C7H7NO
• Molecular Weight: 121.14
• Product Categories: ALDEHYDE;pharmacetical;Pyridines
• Mol File: 74663-96-0.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 230.2 °C at 760 mmHg
• Flash Point: 98.5 °C
• Appearance: /
• Density: 1.095 g/cm³
• Vapor Pressure: 0.0668mmHg at 25°C
• Refractive Index: 1.563
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 3.55±0.18(Predicted)
• CAS DataBase Reference: 3-METHYL-4-PYRIDINECARBOXALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHYL-4-PYRIDINECARBOXALDEHYDE(74663-96-0)
• EPA Substance Registry System: 3-METHYL-4-PYRIDINECARBOXALDEHYDE(74663-96-0)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-41-37/38-22
• Safety Statements: 26-36/37/39-39
• HazardClass: IRRITANT
• Hazardous Substances Data: 74663-96-0(Hazardous Substances Data)

Usage

General Description

3-methyl-4-pyridinecarboxaldehyde, also known as 3-methylisonicotinaldehyde, is a chemical compound with the molecular formula C7H7NO. It is a yellow to brown solid with a strong, sweet, caramel-like odor. This chemical is commonly used as a flavoring agent in the food industry and as a fragrance ingredient in the cosmetic and personal care products industry. It is also used in the synthesis of pharmaceuticals and other organic compounds. 3-methyl-4-pyridinecarboxaldehyde is considered to be a versatile building block in organic synthesis due to its reactive aldehyde group, making it an important compound in the chemical and pharmaceutical industries.

InChI:InChI=1/C7H7NO/c1-6-4-8-3-2-7(6)5-9/h2-5H,1H3

Upstream product

• 583-58-4 3,4-Lutidin 
• 72990-37-5 3-chloro-4-pyridinecarboxyaldehyde 
• 823-96-1 Trimethylboroxine 
• 88329-56-0 3,N-dimethylisonicotinanilide 

Downstream Products

• 222191-28-8 3-methyl-pyridine-4-carbaldehyde oxime 
• 1604771-53-0 C₁₇H₁₅F₃N₂O 
• 7584-05-6 3-methyl-4-cyanopyridine 

Relevant articles and documents

Meso-Pyridyl BODIPYs with tunable chemical, optical and electrochemical properties

A series of meso-pyridyl substituted BODIPY molecules has been synthesized, characterized and their optical and electrochemical properties compared. By utilizing ethanol and dichloromethane during the initial condensation reactions, there is a significant increase in the isolated yields compared to standard protocols. The properties of the highly fluorescent BODIPYs could be tuned by modifying the substituents of the pyridine, leading to pyridyl BODIPY as prospective ligands for future metal complexes. Furthermore, the presented BODIPY derivatives are shown to be applicable for fluorescence pH sensing over selective pH ranges.

Copper-catalyzed selective oxygenation of methyl and benzyl substituents in pyridine with O2

A selective oxygenation of picolines and their derivatives has been achieved by usingasimple copper salt as a catalyst and molecular oxygen as an oxidant, where the α-position of the alkyl substituent is selectively oxidized to give the corresponding aldehydes or ketones. Addition of a catalytic amount of water enhances the catalytic activity, which could be attributed to the role of the proton donor to activate the substrates.

Optimization of the aromatase inhibitory activities of pyridylthiazole analogues of resveratrol

Aromatase is an established target not only for breast cancer chemotherapy, but also for breast cancer chemoprevention. The moderate and non-selective aromatase inhibitory activity of resveratrol (1) was improved about 100-fold by replacement of the ethyl