746670-90-6Relevant articles and documents
Enantioselective synthesis of benzyl (1S,2R,4R)-4-(tert- butoxycarbonylamino)-2-(hydroxymethyl)-cyclohexylcarbamate using an iodolactamization as the key step
Campbell, Carlton L.,Hassler, Carla,Ko, Soo S.,Voss, Matthew E.,Guaciaro, Michael A.,Carter, Percy H.,Cherney, Robert J.
, p. 6368 - 6370 (2009)
(Chemical Equation Presented) An efficient enantioselective synthesis of benzyl (1S,2R,4R)-4-(tert-butoxycarbonylamino)-2-(hydroxymethyl) cyclohexylcarbamate 2, an essential intermediate for a series of potent CCR2 antagonists, is described. The key step
Cyclic derivatives as modulators of chemokine receptor activity
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Page/Page column 36, (2008/06/13)
The present application describes modulators of MCP-1 of formula (I): or pharmaceutically acceptable salt forms thereof, useful for the treatment of rheumatoid arthritis, multiple sclerosis, atherosclerosis and asthma.