746675-00-3Relevant academic research and scientific papers
Synthesis, characterization, and biological study of phenylalanine amide derivatives
Bhat, Mahesh,Belagali,Rajesh Shastry,Ravishankar Rai
, p. 2001 - 2008 (2016)
In the present study, a series of amide derivatives of 4-nitro-l-phenylalanine were synthesized with good yield from 4-nitro-l-phenylalanine and substituted anilines using propylphosphonic anhydride (T3P) as coupling reagent and were characterized through the IR, LC–MS, 1H and 13C NMR spectral studies. The isolated products were screened for antimicrobial and antioxidant activities. Some of the compounds showed Microsporum gypsuem activity or were active against Candida albicans, also a few of compounds showed antibacterial activities. The resultant compounds screened for anti-oxidant activity, which showed good activity for DPPH scavenging and ABTS assay methods and others had moderately activity. Some amide compounds act as metal chelating ligands with Fe2+ ions. Graphical abstract: [Figure not available: see fulltext.]
Phenethylamino sulfamic acids
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Page 24, (2010/02/08)
Compounds of formula (I): are effective in the treatment of protein tyrosine phosphatase (PTPase) mediated disorders such as diabetes.
