746677-16-7Relevant academic research and scientific papers
Double C-H activation during functionalization of phenyl(methyl)ketene on iridium(I) using alkynes. Synthesis of 1,4-dien-3-ones
Grotjahn, Douglas B.,Hoerter, Justin M.,Hubbard, John L.
, p. 8866 - 8867 (2004)
Under the influence of an Ir(I) metal fragment, the methyl group of phenyl(methyl)ketene undergoes two C-H activations in reacting with internal alkynes, giving metallacycles 3 in 86-94% yield. Treatment of 3 with CO liberates 1,4-dien-3-ones 5 in 81-93% yield, along with CO complex 4. A possible mechanism for the very selective double C-H activation-alkyne coupling is discussed. Copyright
