74676-47-4

Basic information

• Product Name: N,N',N'',N'''-tetratosyl-1,10-diamino-4,7-diazadecane
• Synonyms: N,N',N'',N'''-tetratosyl-1,10-diamino-4,7-diazadecane
• CAS NO: 74676-47-4
• Molecular Weight: 791.047
• Mol File: 74676-47-4.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: N,N',N'',N'''-tetratosyl-1,10-diamino-4,7-diazadecane(CAS DataBase Reference)
• NIST Chemistry Reference: N,N',N'',N'''-tetratosyl-1,10-diamino-4,7-diazadecane(74676-47-4)
• EPA Substance Registry System: N,N',N'',N'''-tetratosyl-1,10-diamino-4,7-diazadecane(74676-47-4)

Safety Data

• Hazardous Substances Data: 74676-47-4(Hazardous Substances Data)

Upstream product

• 10563-26-5 N,N'-bis(3-aminopropyl)-1,2-diamine 
• 98-59-9 p-toluenesulfonyl chloride 
• 7732-18-5 water 
• 36394-60-2 3,8-dioxo-4,7-diazadecanediamide 
• 477808-21-2 N-[2-(2-methoxycarbonyl-acetylamino)-ethyl]-malonamic acid methyl ester 

Downstream Products

• 74676-48-5 1,5,8,12-N,N',N'',N'''-terakis(p-toluenesulfonyl)tetraazacyclohexadecane 
• 148873-87-4 N,N',N'',N'''-tetrakistosyl-2,6,9,13-tetraaza<14>paracyclophane 
• 129886-67-5 1,4,7,10,14,17-Hexakis-(toluene-4-sulfonyl)-1,4,7,10,14,17-hexaaza-cycloicosane 
• 180678-12-0 4,8,11,15-Tetrakis(p-tolylsulfonyl)-4,8,11,15-tetraazaoctadecane-1,18-diamine 
• 15439-16-4 1,4,8,12-Tetraazacyclopentadecan 
• 295-37-4 1,4,8,11-Tetraazacyclotetradecane 
• 334528-87-9 N,N',N'',N'''-tetratosyl-2,6,9,13-tetraaza[14]metacyclophane 
• 69038-12-6 1,4,8,12-tetrakis(p-tolylsulphonyl)-1,4,8,12-tetra-azacyclopentadecane 
• 120808-62-0 7,11,14,18-tetrakis(p-tolylsulphonyl)-1,4-dioxa-7,11,14,18-tetra-azacycloicosane 
• 77320-31-1 1,4,7,11,14-pentatosyl-1,4,7,11,14-pentaazacycloheptadecane 
• 71089-74-2 1,4,8,11-tetrakis(p-toluenesulphonyl)-1,4,8,11-tetraazacyclotetradecane 
• 150059-50-0 16,17,19,20-Tetramethyl-N,N',N'',N'''-tetratosyl-2,6,9,13-tetraaza<14>paracyclophane 
• 120808-63-1 10,14,17,21-tetrakis(p-tolylsulphonyl)-1,4,7-trioxa-10,14,17,21-tetra-azacyclotricosane 
• 120808-61-9 4,8,11,15-tetrakis(p-tolylsulphonyl)-1-oxa-4,8,11,15-tetraazacycloheptadecane 

Relevant articles and documents

ARENE CONNECTED POLYAMINE MACRORING DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL USES THEREOF

Abstract: The present invention relates to arene connected polyamine macrocyclic derivatives represented by general formula I, pharmaceutically acceptable salts or hydrates thereof which have anti-HIV activities, in which the definitions of substituents are as defined in the description; to preparation methods of the compounds of formula I; to pharmaceutical compositions containing the compounds of formula I or their pharmaceutically acceptable salts or hydrates; to the use of the compounds of formula I or their pharmaceutically acceptable salts or hydrates for the preparation of a medicament for the treatment and prevention of HIV-associated diseases.

Chemoenzymatic syntheses of polyamines and tetraazamacrocycles

Syntheses of different open chain polyamines starting from enzymatically prepared bis(amidoesters) are described. Some of these polyamines are also used as precursors in the syntheses of tetraazamacrocycles. This methodology can also be applied to the synthesis of chiral compounds.

Methods of preparing manganese complexes of nitrogen-containing macrocyclic ligands

The present invention is directed to low molecular weight mimics of superoxide dismutase (SOD) represented by the formula: STR1 wherein R, R', R1, R'1, R2, R'2, R3, R'3, R4, R'4, R5, R'5, R6, R'6, R7, R'7, R8, R'8, R9, and R'9 and X, Y, Z and n are as defined herein, useful as therapeutic agents for inflammatory disease states and disorders, ischemic/reperfusion injury, stroke, atherosclerosis, hypertension and all other conditions of oxidant-induced tissue damage or injury.