74714-17-3Relevant academic research and scientific papers
Reaction of Push-Pull Enaminoketones and in Situ Generated ortho-Quinone Methides: Synthesis of 3-Acyl-4H-chromenes and 2-Acyl-1H-benzo[f]chromenes as Precursors for Hydroxybenzylated Heterocycles
Lukashenko, Anton V.,Osyanin, Vitaly A.,Osipov, Dmitry V.,Klimochkin, Yuri N.
, p. 1517 - 1528 (2017/02/10)
A simple and efficient method for the synthesis of 4H-chromenes and 1H-benzo[f]chromenes containing a trifluoroacetyl or aroyl group in the pyran ring from o-quinone methide precursors and push-pull enaminoketones has been developed. The chromenes are presumably formed through an initial oxa-Diels-Alder reaction, followed by an elimination of amine. The possibility of further transformations of given chromenes to o-hydroxybenzylated pyrazoles, isoxazoles, and pyridines has been demonstrated.
STUDIES IN PHENOLIC MANNICH BASES - REACTION WITH ACETYLENES
Balasubramanian, K. K.,Selvaraj, S.
, p. 851 - 852 (2007/10/02)
3-Formyl, 3-benzoyl and 2,3-dibenzoyl-4H-Chromenes have been synthesised by the reaction of phenolic Mannich bases with electron-deficient acetylenic systems.
