74726-83-3

Upstream product

• 15146-94-8 5-chloro-2-pentanol 
• 201230-82-2 carbon monoxide 
• 74726-78-6 1-iodo-2-phenylthiomethyl-4,6-dimethoxy-benzene 
• 2150-37-0 methyl 3,5-dimethoxybenzoate 
• 19491-18-0 methyl 2-bromo-3,5-dimethoxybenzoate 
• 74726-76-4 2-bromo-3,5-dimethoxybenzyl alcohol 
• 246871-23-8 1-Chloromethyl-2-iodo-3,5-dimethoxy-benzene 
• 74726-77-5 2-iodo-3,5-bis(methoxy)benzenemethanol 

Downstream Products

• 84574-15-2 2-[6-Cyano-6-(1-ethoxy-ethoxy)-1-phenylsulfanyl-hexyl]-4,6-dimethoxy-benzoic acid 4-iodo-1-methyl-butyl ester 
• 84574-16-3 11-(1-Ethoxy-ethoxy)-2,4-dimethoxy-7-methyl-5-oxo-16-phenylsulfanyl-7,8,9,10,11,12,13,14,15,16-decahydro-5H-6-oxa-benzocyclotetradecene-11-carbonitrile 
• 84574-17-4 11-Hydroxy-2,4-dimethoxy-7-methyl-5-oxo-16-phenylsulfanyl-7,8,9,10,11,12,13,14,15,16-decahydro-5H-6-oxa-benzocyclotetradecene-11-carbonitrile 
• 84574-18-5 2,4-Dimethoxy-7-methyl-16-phenylsulfanyl-7,8,9,10,13,14,15,16-octahydro-12H-6-oxa-benzocyclotetradecene-5,11-dione 
• 17194-80-8 Zearalenone Dimethyl Ether 

Relevant academic research and scientific papers

AN IMPORTANT ROLE PLAYED BY DIANIONES IN THE HIGHLY EFFICIENT MACROCYCLE FORMATION BY AN INTRAMOLECULAR ALKYLATION METHOD: APPLICATION TO THE SYNTHESIS OF ZEARALENONE

A new synthetic method for macrolides based on intramolecular alkylation of dianions, generated from phenylthiomethyl group and protected cyanohydrin, is reported.The use of dianions for the cyclization has several characteristic features; (1) Control of

A GENERAL SYNTHETIC METHOD FOR ORSELLINIC ACID MOIETY OF MACROLIDES BY THE PALLADIUM-CATALYZED CARBONYLATION OF ARYL IODIDE AND ITS APPLICATION TO ZEARALENONE SYNTHESIS

Palladium-catalyzed carbonylation of 1-iodo-2-phenylthiomethyl-4,6-dimethoxybenzene (9) with 10-iodo-6,2'-dioxolane-2-decanol (10) afforded the corresponding ω-iodoalkyl ester of 2-phenylthiomethyl-4,6-dimethoxybenzoate (3) in 70percent yield, which