74732-51-7Relevant academic research and scientific papers
Metal- and Base-Free Room-Temperature Amination of Organoboronic Acids with N-Alkyl Hydroxylamines
Sun, Hong-Bao,Gong, Liang,Tian, Yu-Biao,Wu, Jin-Gui,Zhang, Xia,Liu, Jie,Fu, Zhengyan,Niu, Dawen
, p. 9456 - 9460 (2018)
We have found that readily available N-alkyl hydroxylamines are effective reagents for the amination of organoboronic acids in the presence of trichloroacetonitrile. This amination reaction proceeds rapidly at room temperature and in the absence of added metal or base, it tolerates a remarkable range of functional groups, and it can be used in the late-stage assembly of two complex units.
Aliphatic lmines in titanium-mediated reductive cross-coupling: unique reactivity of Ti(O-i-Pr)-BuLi
Tarselli, Michael A.,Mlcalizio, Glenn C.
supporting information; experimental part, p. 4596 - 4599 (2009/12/09)
A procedure for the coupling of aliphatic lmlnes with allyllc and alienle alkoxldes Is described. The success of these studies was enabled by a unique reactivity profile of TI(IV) IsopropoxIde/n-BuLI compared to well-known TI(IV) IsopropoxIde/RMgX systems
