74733-67-8

Upstream product

• 1571-08-0 methyl 4-formylbenzoate 
• 232595-00-5 methyl (E)-4-(2-nitroprop-1-en-1-yl)benzoate 

Downstream Products

• 113733-68-9 N-[2-(4-carbomethoxyphenyl)-1-methylethyl]-2-hydroxy-2-(2-trifluoromethyl-thiazol-4-yl)ethanamine 
• 1035269-33-0 4-(2-aminopropyl)-N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]benzamide 
• 99719-84-3 methyl 4-<2-<(2-hydroxy-3-phenoxypropyl)amino>-2-methylethyl>benzoate 

Relevant academic research and scientific papers

P300/CBP HAT INHIBITORS

Provided are compounds of Formula (I): and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with histone acetyltransferase (HAT).

Novel arylethanolamines for promoting livestock production

The growth of livestock is promoted by the novel arylethanolamines of the formula STR1 in which R1 represents cyano, R2 represents amino, alkylamino or acylamino, R3 represents hydrogen, halogen, alkyl, halogenoalkyl, alkoxy, halogenoalkoxy, hydroxymethyl, nitro or methylsulphonylmethyl, R4 represents hydrogen, alkyl or acyl, R5 represents hydrogen or alkyl, R6 represents alkyl, n represents 1, 2 or 3, R7 represents the radicals --COR9, --O-alkylene-COR9, -alkylene-R10 or --O-alkylene-R10, R8 represents hydrogen, alkyl or halogen, R9 represents hydroxyl, alkoxy or the radical --NR11 R12, R10 represents hydroxyl, alkoxy or the radical NR11 R12, R11 represents hydrogen or alkyl, and R12 represents hydrogen or alkyl, and the physiologically acceptable salts thereof.

Secondary amines, their preparation and use in pharmaceutical compositions

The compounds of the formula (II): STR1 and their pharmaceutically acceptable salts wherein R1 is a hydrogen, fluorine or chlorine atom or a hydroxyl, hydroxymethyl, methyl, methoxyl, amino, formamido, acetamido, methylsulphonylamido, nitro, benzyloxy, methylsulphonylmethyl, ureido, trifluoromethyl or p-methoxybenzylamino group; R2 is a hydrogen, fluorine or chlorine atom or a hydroxyl group; R3 is a hydrogen or chlorine atom or a hydroxyl group; R4 is a carboxylic acid group or a salt, ester or amide thereof; R5 is a hydrogen, chlorine or fluorine atom or a methyl, methoxyl or hydroxyl group or a carboxylic acid group or a salt, ester or amide thereof; R6 is a hydrogen atom or a methyl, or propyl group; X is an oxygen atom or a bond; and Y is an alkylene group of up to 6 carbon atoms or a bond have been found to possess anti-obesity and/or antihyperglycaemic activity.