74760-01-3Relevant academic research and scientific papers
Chemistry and Pharmacology of the Non-Benzodiazepine Anxiolytic Enciprazine and Related Compounds
Engel, Juergen,Fleischhauer, Ilona,Jakovlev, Vladimir,Kleemann, Axel,Kutscher, Bernhard,et al.
, p. 2976 - 2981 (2007/10/02)
In the course of studies on tranquilizers, new non-benzodiazepine-like compounds were synthesized.These are 1-(3,4,5-trimethoxyphenoxy)-3-propan-2-ol (INN: enciprazine) and derivatives thereof which were screened pharmacologically in order to evaluate their central nervous system activity.Compounds with marked antiaggressive and anxiolytic properties but without dependence potential could be detected.Enciprazine was selected for clinical investigations.
