7477-68-1

Usage

Molecular Weight

329.44 g/mol

Structure

A derivative of prop-2-en-1-one (Acetophenone) with a piperidine group and multiple phenyl groups attached.

Functional Groups

Carbonyl group (C=O) in the prop-2-en-1-one core
Aromatic rings (Phenyl groups) attached to the core
A cyclic amine (Piperidine group) attached to the core

Appearance

Likely a solid or oily liquid, depending on the conditions

Solubility

Soluble in organic solvents like ethanol, methanol, and dichloromethane

Stability

Stable under normal conditions, but sensitive to heat, light, and moisture

Reactivity

Can undergo reactions typical of carbonyl compounds, such as nucleophilic addition, reduction, and condensation reactions

Biological Activity

Potential biological activity, depending on the specific application and context

Applications

Commonly used in pharmaceutical research and organic synthesis due to its unique structure

Hazards

Potential irritant or toxic, depending on the dose and exposure route; proper handling and safety precautions are necessary

Storage

Should be stored in a cool, dry, and well-ventilated area, away from heat and light sources, and in a sealed container to prevent degradation or contamination.

Upstream product

• 110-89-4 piperidine 
• 7338-94-5 1,3-diphenyl-2-propynone 
• 145930-96-7 (2-Oxo-2-phenyl-ethyl)-[1-phenyl-1-piperidin-1-yl-meth-(E)-ylidene]-sulfonium; bromide 
• 6935-75-7 2-bromo-1,3-diphenyl-2-propen-1-one 
• 64-17-5 ethanol 
• 611-91-6 2,3-dibromo-1,3-diphenylpropane-1-one 
• 70-11-1 α-bromoacetophenone 
• 15563-40-3 N-thiobenzoylpiperidine 

Downstream Products

• 120-46-7 1,3-diphenylpropanedione 
• 58327-74-5 4,6-diphenyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile 

Relevant academic research and scientific papers

Dual mechanism of enamine-enamine rearrangement of 1,3-diaryl-3-(1-imidazolyl)propen-2-ones

The formation of 1,3-diaryl-3-(1-imidazolyl)propen-1,3-diol that is an intermediate of enamine-enamine rearrangement of 1,3-diaryl-3-(1-imidazolyl)propen-1-ones constitutes the key stage of the dual mechanism of the rearrangement proper. The reaction of 1,3-diaryl-2,3-dibromopropan-1-ones with a primary amine provides 1,3-diaryl-3-iminopropan-1-ones as a result of enamine-imine prototropic rearrangement.

STUDY OF THE ESCHENMOSER SULFIDE CONTRACTION METHOD WITH AND WITHOUT A THIOPHILE

Results obtained and observations made by applying the title method for the synthesis of enaminones 5a-o, using triphenylphosphine as a thiophile and triethylamine as a base, are reported.The product distributions of the deprotonations of α-phenacylthio iminium bromides with and without thiophile and those known from thiouronium and heterocyclic thionium analogs are compared.Key words: Enaminones; α-phenacylthio iminium bromides; disulfides; thiiranes.

TRISUBSTITUTED THIAZOLES BY A 6?-ELECTROCYCLIZATION OF IMINOTHIOCARBONYL YLIDES

Iminothiocarbonyl ylides are generated by a sulfur ligand exchange reaction of sulfonium salts and undergo a 6?-electrocyclic closure and aromatization to tri substituted thiazoles.Related carbonyl ylides preferred a 4?-electrocyclization.