74787-38-5Relevant academic research and scientific papers
Synthesis of 5-[4,5-13C2]- and 5-[1,5-13C2]aminolevulinic acid
Iida, Katsumi,Tokiwa, Shinji,Ishii, Toshihiro,Kajiwara, Masahiro
, p. 569 - 576 (2007/10/03)
5-[4,5-13C2]- and 5-[1,5-13C2]Aminolevulinic acid (ALA) have been synthesized by the Gabriel condensation of potassium phthalimide with ethyl bromo [1,2-13C2]acetate (derived from [1,2-13C2]acetic acid) or ethyl bromo[2-13C]-acetate (derived from sodium [2-13C]acetate), followed by conversion to the chloride, coupling reaction with 2-ethoxycarbonylethylzinc iodide derived from ethyl 3-iodopropionate or 2-methoxy[13C]carbonylethylzinc iodide derived from methyl 3-iodo[1-13C]propionate (generated from potassium [13C]cyanide), and hydrolysis. Copyright
An asymmetric synthesis of L-[2-13C]aspartic acid from sodium E2-13C]acetate
Takatori, Kazuhiko,Nishihara, Mikiko,Kajiwara, Masahiro
, p. 701 - 708 (2007/10/03)
L-[2-13C]Aspartic acid was synthesized by using Dellaria's oxazinone labelled with 13C at the 3-position, prepared from phenyl [2-13C]bromoacetate, and (S)-2-phenylglycinol, as a chiral glycine equivalent. Phenyl [2-1
