74793-10-5Relevant academic research and scientific papers
Facile Synthesis of 3-Methyl-5,6-dihydro-2H-pyran-2-ones and 3-Methylcoumarines under Mild Conditions
Falsone, Gioacchino,Spur, Bernd,Wingen, Peter H.
, p. 763 - 766 (2007/10/02)
The synthesis of the 3-methyl-5,6-dihydro-2H-pyran-2-one, 3, 5 and the 3-methylcoumarines 7a-e from the β-hydroxyoxo compounds 1,4,6a-c and the phosphonopropionic acid 2 under Wittig-Horner conditions is described.
THE REACTION OF ENOLS WITH SUPEROXIDE ANION RADICAL 2-.>. SYNTHESIS OF 2,3-UNSATURATED-δ-VALEROLACTONES.
Frimer, Aryeh A.,Gilinsky-Sharon, Pessia,Aljadeff, Gladis
, p. 1301 - 1304 (2007/10/02)
3- and 4-Hydroxycoumarin (1 and 3) as well as 2-hydroxy-2,5-cyclohexadien-1-ones 5a-f were reacted with KO2/18-crown-6 in benzene.Initial deprotonation of the enol hydrogen was followed by nucleophilic attack by O2> (for 1 and 3) and/or autoxidation of the resulting anion (for 1 and 5a-e).A convenient synthesis of 2,3-unsaturated-δ-valerolactones from the corresponding 2-cyclohexen-1-ones is also described.
