74805-91-7 Usage
Chemical Properties
Methylophiopogonanone B is soluble in methanol, ethanol, DMSO and other organic solvents, and is derived from the fibrous root of Ophiopogon japonicus.
Uses
Methylophiopogonanone B has the effect of enhancing protease activity and regulating cytoskeleton remodeling.
Check Digit Verification of cas no
The CAS Registry Mumber 74805-91-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,8,0 and 5 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 74805-91:
(7*7)+(6*4)+(5*8)+(4*0)+(3*5)+(2*9)+(1*1)=147
147 % 10 = 7
So 74805-91-7 is a valid CAS Registry Number.
74805-91-7Relevant articles and documents
First synthesis of racemic methylophiopogonanone B and its inhibitory activity of hypoxia-inducible factor-1α
Fujii, Mikio,Egawa, Kiyoshi,Hirai, Yasuaki,Kondo, Masato,Akita, Hiroyuki,Nose, Kiyoshi,Toriizuka, Kazuo,Ida, Yoshiteru
, p. 207 - 212 (2009)
Methylophiopogonanone B, a constituent of Ophiopogonis tuber, found to be a potent inhibitor of hypoxia induced factor-1 α (HIF-1 α) activity, was synthesized from 2,4,6-trihydroxy-3,5-dimethylacetophenone in 57% yield. The synthetic methylophiopogonanone
