748109-16-2Relevant academic research and scientific papers
IRL 2500: A potent ET(B) selective endothelin antagonist
Frueh,Saika,Svensson,Pitterna,Sakaki,Okada,Urade,Oda,Fujitani,Takimoto,Yamamura,Inui,Makatani,Takai,Umemura,Teno,Toh,Hayakawa,Murata
, p. 2323 - 2328 (2007/10/03)
Combination of a glycine substitution scan on the C-terminal dodecapeptide analog of ET-1 and a substance P antagonist screen on the basis of a homology study of the rhodopsin superfamily of seven-transmembrane receptors yielded in the development of IRL 2500, a potent ET(B) selective endothelin antagonist.
