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Ulicyclamide is a synthetic chemical compound with the molecular formula C15H21N3O2. It is a potent and selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4), which plays a crucial role in the regulation of glucose homeostasis. By inhibiting DPP-4, ulicyclamide helps to increase the levels of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), two incretin hormones that stimulate insulin secretion and reduce glucagon release, ultimately leading to improved blood glucose control. This makes ulicyclamide a potential therapeutic agent for the treatment of type 2 diabetes.

74839-81-9

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74839-81-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 74839-81-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,8,3 and 9 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 74839-81:
(7*7)+(6*4)+(5*8)+(4*3)+(3*9)+(2*8)+(1*1)=169
169 % 10 = 9
So 74839-81-9 is a valid CAS Registry Number.
InChI:InChI=1/C33H39N7O5S2/c1-5-17(2)25-32-37-22(16-47-32)27(41)34-18(3)31-36-23(15-46-31)28(42)35-21(14-20-10-7-6-8-11-20)33(44)40-13-9-12-24(40)30-39-26(19(4)45-30)29(43)38-25/h6-8,10-11,15-19,21,24-26H,5,9,12-14H2,1-4H3,(H,34,41)(H,35,42)(H,38,43)

74839-81-9Upstream product

74839-81-9Relevant academic research and scientific papers

A FACILE SYNTHESIS OF ULICYCLAMIDE

Sugiura, Tsuneyuki,Hamada, Yasumasa,Shioiri, Takayuki

, p. 2251 - 2254 (2007/10/02)

Ulicyclamide (1), a cytotoxic cyclic peptide from a marine tunicate, has been efficiently synthesized by the solid-phase method using diethyl phosphorocyanidate for the coupling and trimethylsilyl triflate for the final deprotection.

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