748799-33-9

Basic information

• Product Name: 5-amino-1-methyl-2-phenylindole
• Synonyms: 5-amino-1-methyl-2-phenylindole
• CAS NO: 748799-33-9
• Molecular Weight: 222.29
• Mol File: 748799-33-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 5-amino-1-methyl-2-phenylindole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-amino-1-methyl-2-phenylindole(748799-33-9)
• EPA Substance Registry System: 5-amino-1-methyl-2-phenylindole(748799-33-9)

Safety Data

• Hazardous Substances Data: 748799-33-9(Hazardous Substances Data)

Upstream product

• 20870-79-5 5-nitrooxindole 
• 31521-56-9 1-methyl-5-nitro-2-phenyl-1H-indole 

Downstream Products

• 748799-39-5 4,4,4-trifluoro-3-oxobutyric acid N-(1-methyl-2-phenyl-1H-5-indolyl)amide 

Relevant articles and documents

FUSED RING COMPOUND HAVING UREA STRUCTURE

The present invention relates to a novel fused ring compound having urea structure that exhibits excellent NAMPT activating effect, and a method using the same for treating / preventing metabolic disorder, cardiovascular and kidney disease, mitochondrial disease, neurodegenerative disease, ocular disease, and muscle wasting disorder. The present invention provides a compound represented by following formula (I) or a pharmacologically acceptable salt: Formula (I) wherein A, B, R, R2 and R3 represent the same meanings as in the claims.

2-ARYLINDOLE DERIVATIVES AS NPGES-I INHIBITORS

A 2-arylindole compound substituted in position 5, of formula (I): in which X, Y, Z, W, A, R and R' have the meanings given in the description, a pharmaceutical composition comprising it, and also intermediate compounds and a preparation process therefor.

Novel anti-inflammatory and analgesic heterocyclic amidines that inhibit nitrogen oxide (NO) production

Heterocyclic amidines with anti-inflammatory and analgesic activity that inhibit nitrogen oxide production, of formula (I): in which: G1 and G2 are hydrogen, halogen, hydroxyl, C1-C4 alkoxy, C1-C4 alkyl, and an amidino substituent of formula Q, provided that, for each compound of formula (I), only one of the two substituents G1 or G2 is an amidino substituent of formula Q: and in which the substituents W, Y and X are combined to form 9- or 10-membered bicyclic heteroaromatic derivatives containing up to 2 hetero atoms in the same ring; and Z is an aryl or heteroaryl group, a linear or branched C1-C6 alkyl or alkenyl chain, a C1-C4 alkyl-aryl group or a C1-C4 alkyl-heteroaryl group.