748810-20-0Relevant academic research and scientific papers
Synthesis of New Pyrrolo[2, 3-b]pyridines as a Potent Inhibitor of Tumour Necrosis Factor Alpha
Mohammed, Khalid,Hilmy, Hassan
, p. 15 - 19 (2007/10/03)
The MAP kinase p38 plays a key role in the biosynthesis of the inflammatory cytokines tumor necrosis factor α (TNF-α) and 1L-1β. Accordingly, new pyrrolo[2,3]pyridine derivatives 5 a-d were prepared from 2-amino-3-cyanopyrroles 3 a-d via the intermediate
