74893-31-5

Basic information

• Product Name: BOC-3-(3-BENZOTHIENYL)-DL-ALANINE
• Synonyms: RARECHEM AK ML 0061;BOC-3-(3-BENZOTHIENYL)-DL-ALANINE;3-(benzo[b]thiophen-3-yl)-2-(tert-butoxycarbonylamino)propanoic acid
• CAS NO: 74893-31-5
• Molecular Formula: C₁₆H₁₉NO₄S
• Molecular Weight: 321.39
• Mol File: 74893-31-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BOC-3-(3-BENZOTHIENYL)-DL-ALANINE(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-3-(3-BENZOTHIENYL)-DL-ALANINE(74893-31-5)
• EPA Substance Registry System: BOC-3-(3-BENZOTHIENYL)-DL-ALANINE(74893-31-5)

Safety Data

• Hazardous Substances Data: 74893-31-5(Hazardous Substances Data)

Usage

General Description

BOC-3-(3-benzothienyl)-DL-alanine is a compound used in the synthesis of peptides and amino acid derivatives. It is a derivative of the amino acid alanine, with a benzothienyl group attached to the third carbon atom. The BOC (tert-butoxycarbonyl) protecting group is often added to the amino group of alanine to prevent unwanted reactions during peptide synthesis. BOC-3-(3-BENZOTHIENYL)-DL-ALANINE is commonly used in the pharmaceutical and biotechnology industries for the production of custom peptides and other bioactive molecules. Its unique structure and properties make it an important building block for the synthesis of complex molecules and pharmaceutical compounds.

Upstream product

• 123-91-1 1,4-dioxane 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1026538-48-6 3-Benzo[b]thiophen-3-yl-N¹-(2-methoxy-benzyl)-propane-1,2-diamine 
• 1060667-52-8 3-Benzo[b]thiophen-3-yl-2-tert-butoxycarbonylamino-propionic acid 3,5-bis-trifluoromethyl-benzyl ester 

Relevant articles and documents

HETEROCYCLIC AMIDE DERIVATIVES AS TACHYKININ ANTAGONISTS

Compounds of formula (I), and salts and prodrugs thereof, wherein Q. sup.1 is phenyl substituted by one or more halo; optionally substituted naphthyl, indolyl, benzothiophenyl, benzofuranyl, benzyl or fluorenyl; the dotted line represents an optional covalent bond; one of X and Y is H and the other is hydroxy or C 1-6 alkoxy, or X and Y together form a group =O or =NOR 5 where R 5 is H or C. sub.1-6 alkyl; R. sup.1 is H or C 1-6 alkyl. R 2 is CO--W--R 6 where W represents a bond or a hydrocarbon chain of 1-6 carbon atoms and R 6 is an azacyclic or azabicyclic group; R 3 is H, C 1-6 alkyl or C. sub.2-6 alkenyl; and R 4 is phenyl optionally substituted by 1-3 of C. sub.1-6 alkyl, C. sub.2-6 alkenyl, C 2-6 alkynyl, halo, cyano, nitro, trifluoromethyl, trimethylsilyl, OR a, SR a, SOR. sup.a, NR a R b, NR a COR b, NR a CO 2 R b, CO 2 R a or CONR a R. sup.b, where R a and R b are H, C 1-6 alkyl, phenyl or trifluoromethyl; are tachykinin antagonists useful in therapy.

HETEROCYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Compounds of formula (I), and salts and prodrugs thereof STR1 wherein Q 1 is halo substituted phenyl; naphthyl; indolyl; benzthiophenyl; benzofuranyl; benzyl; or fluorenyl; . . is an optional covalent bond;one of X and Y is H and the other is