74896-60-9

Usage

General Description

1-Propanone, 1-phenyl-3,3-bis[(phenylmethyl)thio]-, also known as benzoylthiobenzylthioacetone, is a chemical compound primarily used as a fragrance ingredient in personal care products and perfumes. It is a pale yellow liquid with a strong, sweet, and floral odor. 1-Propanone, 1-phenyl-3,3-bis[(phenylmethyl)thio]- is often utilized in the manufacturing of cosmetics, soaps, and other beauty products due to its pleasant scent. Additionally, it can also be used as a flavoring agent in food products and as an intermediate in the production of other chemicals. However, it is important to handle this chemical with care, as it can cause skin and eye irritation, and should be used in well-ventilated areas to avoid inhalation.

Upstream product

• 100-53-8 phenylmethanethiol 
• 3623-15-2 phenyl propargyl ketone 
• 42426-91-5 3,3-bis(butylthio)-1-phenylpropan-1-one 

Downstream Products

• 74896-61-0 (E)-3-Benzylsulfanyl-1-phenyl-propenone 

Relevant academic research and scientific papers

Covalent Adaptable Networks with Tunable Exchange Rates Based on Reversible Thiol–yne Cross-Linking

The design of covalent adaptable networks (CANs) relies on the ability to trigger the rearrangement of bonds within a polymer network. Simple activated alkynes are now used as versatile reversible cross-linkers for thiols. The click-like thiol–yne cross-linking reaction readily enables network synthesis from polythiols through a double Michael addition with a reversible and tunable second addition step. The resulting thioacetal cross-linking moieties are robust but dynamic linkages. A series of different activated alkynes have been synthesized and systematically probed for their ability to produce dynamic thioacetal linkages, both in kinetic studies of small molecule models, as well as in stress relaxation and creep measurements on thiol–yne-based CANs. The results are further rationalized by DFT calculations, showing that the bond exchange rates can be significantly influenced by the choice of the activated alkyne cross-linker.

Ionic liquid as catalyst and solvent: the remarkable effect of a basic ionic liquid, [bmIm]OH on Michael addition and alkylation of active methylene compounds

A basic ionic liquid, 1-methyl-3-butylimidazolium hydroxide, [bmIm]OH, catalyzes the Michael addition of active methylene compounds to conjugated ketones, carboxylic esters and nitriles. It further catalyzes the addition of thiols to α,β-acetylenic ketones and alkylation of 1,3-dicarbonyl and -dicyano compounds. The Michael addition to α,β-unsaturated ketones proceeds in the usual way, giving the monoaddition products, whereas addition to α,β-unsaturated esters and nitriles leads exclusively to the bis-addition products. The α,β-acetylenic ketones undergo double conjugate addition with thiols producing β-keto 1,3-dithio-derivatives. In the alkylation reaction the acyclic 1,3-diketones are monoalkylated, whereas cyclic ketones undergo dialkylation under identical conditions. All these reactions were carried out without any organic solvent. The ionic liquid can also be recycled.

Facile synthetic method for the preparation of dithioacetals by the double conjugate addition of acetylenes bearing electronwithdrawing groups with thiols

β, β-Bis(alkylmercapto)propionates were obtained by the reaction of methyl propiolates with 2 equiv. of mercaptanes in the presence of tri-n-butylphosphine in high yield. The corresponding dithioacetals could be also obtained by the conjugate addition of mercaptanes toward methyl β-alkylmercaptoenoates, in which, tri-n-butylphosphine also catalyzed the addition of thiols.