749152-44-1Relevant academic research and scientific papers
Ln[N(SiMe3)2]3-Catalyzed Cross-Diinsertion of C≡N/C≡C into an N-H Bond: Facile Synthesis of 1,2,4-Trisubstituted Imidazoles from Propargylamines and Nitriles
Hong, Longcheng,Shao, Yinlin,Zhang, Lixin,Zhou, Xigeng
, p. 8551 - 8555 (2014/07/21)
A lanthanide-catalyzed sequential insertion of C≡N and C≡C into an N-H bond is presented. The convenient reaction, which proceeds under mild conditions, is an efficient method for preparing 1,2,4-trisubstituted imidazoles directly from readily available propargylamines and nitriles.
Atom-economical synthesis of N-heterocycles via cascade inter-/intramolecular C-N Bond-forming reactions catalyzed by Ti amides
Shen, Hao,Xie, Zuowei
supporting information; experimental part, p. 11473 - 11480 (2010/10/02)
Direct and efficient catalytic reactions with excellent regioselectivity for the preparation of a series of substituted isoindoles, isoquinolines, and imidazoles are reported. Reaction of C6H4(2-CN)C≡C-R with an array of amines, catalyzed by 10 mol % of [σ:η1: η5-(OCH2)(Me2NCH2)C 2B9H9]Ti(NMe2) (1), gives a series of substituted isoindoles in very high yields. In a similar manner, interaction of C6H4(2-CH2CN)C≡C-Ph with various kinds of amines affords a wide range of substituted isoquinolines. On the other hand, treatment of propargylamines (R′C≡CCH2NHR′′) with nitriles in the presence of 10 mol % of 1 produces a class of substituted imidazoles in high yields. A possible reaction mechanism is proposed, involving sequential inter- and intramolecular C-N bond formation via hydroamination/ cyclization reaction of cyanoalkynes with amines or nitriles with propargylamines catalyzed by titanium amides.
Photo-, solvent-, and ion-controlled multichromism of imidazolium- substituted diarylethenes
Nakashima, Takuya,Miyamura, Kentaro,Sakai, Toshiyuki,Kawai, Tsuyoshi
experimental part, p. 1977 - 1984 (2009/09/08)
Cationic diarylethenes with an imidazolium ring are synthesized for the first time. The imidazolium cationic moiety is connected directly to the ethene unit as one of the aryl units that take part in the photoinduced pericyclization reaction. The imidazol
Engineering control over the conformation of the alkyne - Aryl bond by the introduction of cationic charge
Terashima, Takashi,Nakashima, Takuya,Kawai, Tsuyoshi
, p. 4195 - 4198 (2008/02/14)
A novel arylene - ethynyiene molecule has been synthesized. This molecule is more stable in a coplanar form than in a twisted form as in the cases of typical arylene - ethynyiene molecules. When the cationic charge was introduced into the π-conjugated sys
