749253-92-7

Upstream product

• 1186139-46-7 C₃₆H₄₇N₄O₃P 
• 350479-90-2 (S,E)-N-benzylidene-4-methylbenzenesulfinamide 
• 749253-91-6 (S_S,2S,3S)-(+)-ethyl 2-N-(diphenylmethylideneamino)-3-N-(p-toluenesulfinyl)amino-3-phenylpropanoate 

Downstream Products

• 749253-94-9 (4S,5S)-(+)-ethyl 2-oxo-5-phenylimidazolidine-4-carboxylate 

Relevant academic research and scientific papers

Chiral N-phosphonyl imine chemistry: Asymmetric synthesis of α,β-diamino esters by reacting phosphonyl imines with glycine enolates

Chiral phosphonyl imines attached with N-isopropyl protection group were found to react with lithium glycine enolates under convenient conditions to give α,β-diamino esters. Thirteen examples have been examined in good to excellent chemical yields (85-97%

Asymmetric synthesis of syn-(2R,3S)-and anti-(2S,3S)-ethyl diamino-3-phenylpropanoates from N-(benzylidene)-p-toluenesulfinamide and glycine enolates

Addition of differentially N-protected glycine enolates to enantiopure sulfinimines affords syn- and anti-α,β-diamino esters with high diastereoselectivities and good yields.