7494-03-3Relevant academic research and scientific papers
Kepner-Tregoe Decision Analysis as a tool to aid route selection. Part 3. Application to a back-up series of compounds in the PDK project
Parker, Jeremy S.,Bower, John F.,Murray, Paul M.,Patel, Bharti,Talavera, Pere
, p. 1060 - 1077 (2013/01/03)
Kepner-Tregoe Decision Analysis was used to rank 22 potential routes to a back-up series of compounds in the PDK project. The ten highest scoring routes were evaluated practically, affording four new synthetic sequences for preparing the target compounds.
Substituted N-phenyl 2-hydroxy-2-methyl-3,3,3-trifluoropropanamide derivatives which elevate pyruvate dehydrogenase activity
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Page column 55, (2010/02/05)
A compound of formula (I) wherein: n is 1 or 2; R 1 is chloro, fluoro, bromo, methyl or methoxy; R 2 is as defined within; R 3 is as defined within; and R 4 is hydrogen or fluoro; or a pharmaceutically acceptable salt or an in vivo hydrolysable ester thereof is described. The use of compounds of formula (I) in the production of an elevation of PDH activity in a warm-blooded animal such as a human being are also described. Pharmaceutical compositions, methods and processes for preparation of compounds of formula (I) are detailed. STR1
Substituted-4-alkylthioalkane-sulfonanilides and operatives
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, (2008/06/13)
Alkane- and monohaloalkane-sulfonanilides substituted in the para position by alkylthio, alkylsulfinyl and alkylsulfonyl groups and additionally substituted by halogen and optionally by trifluoromethyl and agriculturally acceptable salts thereof are useful herbicides.
