74947-69-6Relevant academic research and scientific papers
Catalytic Enantioselective Cloke–Wilson Rearrangement
Ortega, Alesandere,Manzano, Rubén,Uria, Uxue,Carrillo, Luisa,Reyes, Efraim,Tejero, Tomas,Merino, Pedro,Vicario, Jose L.
supporting information, p. 8225 - 8229 (2018/06/29)
Racemic cyclopropyl ketones undergo enantioselective rearrangement to deliver the corresponding dihydrofurans in the presence of a chiral phosphoric acid as the catalyst. The reaction involves activation of the donor-acceptor cyclopropane substrate by the
Aluminium Oxide Assisted Stereoselective Rearrangement of a Cyclopropyl Ketone to 4,5-Dihydrofuran
Alonso, Miguel E.,Morales, Angelina
, p. 4530 - 4532 (2007/10/02)
Contrary to the general observation that thermally and photochemically induced cyclopropyl ketone to dihydrofuran arrangements take place with partial loss of the stereochemical identity of the starting cyclopropane, a characteristic shared by the closely related vinylcyclopropanes and vinyloxiranes, a case of totally stereospecific, alumina-assisted cyclopropyl ketone to dihydrofuran rearrangement at room temperature was observed.
