74949-65-8 Usage
Chemical structure
A hydrazide derivative composed of a dioxolane ring with a methyl group attached and an acetohydrazide group
Usage
Organic synthesis and pharmaceutical research, particularly in the development of potential drug candidates
Potential applications
Treatment of various diseases and medical conditions
Versatility
A versatile building block for the development of new compounds with biological activity
Ongoing research
Exploration of potential therapeutic uses and improvement of synthesis for broader applications.
Check Digit Verification of cas no
The CAS Registry Mumber 74949-65-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,9,4 and 9 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 74949-65:
(7*7)+(6*4)+(5*9)+(4*4)+(3*9)+(2*6)+(1*5)=178
178 % 10 = 8
So 74949-65-8 is a valid CAS Registry Number.
74949-65-8Relevant academic research and scientific papers
INHIBITORS OF LEUCINE RICH REPEAT KINASE 2
-
Page/Page column 157-158, (2019/02/02)
The present invention relates to novel compounds that inhibit LRRK2 kinase activity, to processes for their preparation, to compositions containing them and to their use in the treatment of or prevention of diseases associated with or characterized by LRRK2 kinase activity, for example Parkinson's disease, Alzheimer's disease and amyotrophic lateral sclerosis (ALS).
New Acetonylsubstituted Azoles, II. 2-Acetonyl-1,2,4-oxadiazoles, 2-Acetonyl-1,3,4-oxadiazoles and 5-Acetonyl-1,2,4-thiadiazoles
Kuebel, Boerries
, p. 793 - 804 (2007/10/02)
3-Acetonyl-1,2,4-oxadiazoles and 2-Acetonyl-1,3,4-oxadiazoles are accessible starting with the ketal of acetoacetamide oxime and the ketal of acetoacetic acid hydrazide, respectively. 5-Acetonyl-1,2,4-thiadiazoles are obtained from 5-chloro-1,2,4-thiadiaz
