7496-21-1

Usage

Uses

Used in Medicinal Chemistry:
(2Z)-2-(4-bromophenyl)-3-[4-(dimethylamino)phenyl]prop-2-enenitrile is utilized as a chemical intermediate in the synthesis of pharmaceutical compounds. Its unique structure and reactivity allow for the development of new drugs with potential applications in treating various diseases and medical conditions.
Used in Materials Science:
In the field of materials science, (2Z)-2-(4-bromophenyl)-3-[4-(dimethylamino)phenyl]prop-2-enenitrile is employed as a building block for the creation of novel materials with specific properties. Its chemical versatility can contribute to the design of advanced materials for applications in electronics, coatings, or other industries that require specialized characteristics.
Used in Chemical Research:
(2Z)-2-(4-bromophenyl)-3-[4-(dimethylamino)phenyl]prop-2-enenitrile serves as a subject of study in chemical research, where its properties and reactivity are explored to understand its behavior under various conditions. This research can lead to new insights and advancements in organic chemistry and related disciplines.

Upstream product

• 16532-79-9 4-Bromophenylacetonitrile 
• 100-10-7 4-dimethylamino-benzaldehyde 

Relevant academic research and scientific papers

(: R)-Binaphthyl derivatives as chiral dopants: Substituent position controlled circularly polarized luminescence in liquid crystals

A series of nonbridged axially chiral binaphthyl derivatives were synthesized and used as chiral dopants for chiral nematic liquid crystals (N?-LCs). It was found that binaphthyl derivatives substituted at 3,3′ positions or 2,2′ positions of binaphthyl rings could induce N?-LCs to show opposite circularly polarized luminescence (CPL) signals, despite having the same configuration. Additionally, a CPL switch could be constructed in these N?-LCs regulated by the applied electric field.

Two Different Emissions of (2Z)-2-(4-Bromophenyl)-3-[4-(dimethylamino)phenyl]prop-2-enenitrile Due to Crystal Habit and Size: Synthesis, Optical, and Supramolecular Characterization

Optical and X-ray diffraction characterizations of crystals I and II of (2Z)-2-(4-bromophenyl)-3-[4-(dimethylamino)phenyl]prop-2-enenitrile (Z-4-BrPhDMAPhACN) are reported. I and II belong to the same monoclinic space group and have nearly identical unit-cell dimensions [I: a = 11.0169(2); b = 6.02041(11); c = 21.8541(4); (β) 98.4082(18). II: a = 11.0475(6); b = 6.0273(3); c = 21.8533(11); (β) 98.315(5)]. Crystals I and II were formed under different conditions and have different crystal habits and colors: crystals I are yellow blocks, whereas crystals II are small, orange needles. I and II show absorption maxima (λabs) in solution at 404 nm and emission (λem) maxima at 501 nm (I) and at 502 nm (II). However, their emission maxima are different in the solid state: I shows an emission at 512 nm and a shoulder at 534 nm, whereas II exhibits a λem maximum at 582 nm. The differences in solid-state photoluminescence were attributed to variations in the crystal morphology and to the crystal habit and size. Both I and II were characterized by nuclear magnetic resonance, mass spectrometry, infrared spectroscopy, UV-vis spectroscopy, fluorescence, cyclic voltammetry, single-crystal and powder X-ray diffraction, differential scanning calorimetry, scanning electron microscopy, and density functional theory calculations.

Optimising molecular rotors to AIE fluorophores for mitochondria uptake and retention

Molecular rotors exhibit fluorescence enhancement in a confined environment and thus have been used extensively in biological imaging. However, many molecular rotors suffer from small Stokes shift and self-aggregation caused quenching. In this work, we have synthesised a series of red emissive molecular rotors based on cationic α-cyanostilbene. Profoundly enhanced aggregation-induced emission (AIE) properties and greatly widened Stokes shifts can be achieved by molecular engineering. With specificity to stain mitochondria, we demonstrate a simple approach to achieve cell uptake and retention upon tuning the pyridinium substituent of the dyes.

Substituent effect on the solid-state photoinduced luminescence of α-cyanostilbene derivatives

Summary: A series of α-cyanostilbene derivatives with aggregation-induced enhanced emission （ AIEE ） was obtained. All the compounds were characterized by UV?vis spectroscopy, fluorescence and nuclear magnetic resonance. These compounds exhibited blue, gr

Biocompatible Fluorescence Nanoparticles and Uses Thereof

The present invention relates to a novel bipolar aryl vinyl compound, nano-probe particles including the same, a contrast agent using the same, and an imaging method thereof. The novel bipolar aryl vinyl compound can adjust the solid-state fluorescence (S

AIE BIOPROBES EMITTING RED OR YELLOW FLUORESCENCE

The present subject matter relates to red emitting mitochondria-targeted aggregation induced emission (AIE) probes as an indicator for membrane potential and mouse sperm activity. The present subject matter relates to AIE-active fluorescent probes for reactive oxygen species (ROS) detection and related biological applications, such as inflammation imaging and glucose assay, as well as the preparation and application of red fluorescent AIEgens.