74963-13-6Relevant academic research and scientific papers
Substituted heterocyclic compound, and use method and use thereof
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Paragraph 0231; 0232; 0233; 0234; 0525; 0526; 0527; 0528, (2016/10/08)
The invention relates to a substituted heterocyclic compound, and a use method and a use thereof. The substituted heterocyclic compound and a medicinal composition including the compound can be used to depress orexin receptors, especially an orexin-1 rece
Electronic Effects of Aryl and Heteroaryl Groups on the Rate of Nucleophilic Displacement of Chlorine from 5-Heteroaryl(or Aryl)-2-chloropyrimidines by Piperidine
Allen, David W.,Buckland, David J.,Hutley, Barrie G.
, p. 463 - 467 (2007/10/02)
The kinetics of nucleophilic displacement of chlorine from a series of 2-chloro-5-heteroaryl(or aryl)pyrimidines by piperidine have been studied in order to assess the electronic effects of the 5-substituent.The observed order of reactivity is 5-(1-methyl
