74979-69-4Relevant academic research and scientific papers
Synthesis and 3D-QSAR study of 1,4-dihydropyridine derivatives as MDR cancer reverters
Radadiya, Ashish,Khedkar, Vijay,Bavishi, Abhay,Vala, Hardevsinh,Thakrar, Shailesh,Bhavsar, Dhairya,Shah, Anamik,Coutinho, Evans
, p. 375 - 387 (2014/02/14)
A series of symmetrical and unsymmetrical 1,4-dihydropyridines were synthesized by a rapid, single pot microwave irradiation (MWI) based protocol along with conventional approach and characterized by NMR, IR and mass spectroscopic techniques. The compound
Novel synthese of heterocycles with N-(1-haloalkyl)azinium halides. Part 5. Preparation of N-substituted 1,4-dihydropyridines
Vanden Eynde,Mayence,Maquestiau,Anders
, p. 3291 - 3304 (2007/10/02)
Thirty N-substituted Hantzsch 1,4-dihydropyridines were prepared under mild and neutral conditions from N-substituted enaminocarbonyl derivatives and aldehydes activated under the form of N-(1-chloroalkyl)pyridinium chlorides by means of thionyl chloride
1-ARYL- AND 1-BENZYL-3,5-DIETHOXYCARBONYL-1,4-DIHYDROPYRIDINES
Sausin, A.E.,Chekavichus, B.S.,Lusis, V.K.,Dubur, G.Ya.
, p. 377 - 385 (2007/10/02)
The possibility has been studied of using anilines in the Hantzsch synthesis.It has been shown that, with the exception of those containing strong electron-accepting substituents, they take part in this reaction with the formation of 1-aryl-1,4-dihydropyridines.The reaction largely depends on the nature of the substituents in the aniline and in the benzaldehyde and is promoted by electron-accepting substituents in the aldehyde and electron-donating substituents in the amine.The mechanism of the reaction is discussed.A number of 1-benzyl-1,4-dihydroxypyridines have been synthesized.The UV, IR, and PMR spectra and the electro-oxidation of the compounds obtained have been studied.
