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5-fluoro-7aH-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine is a chemical compound belonging to the class of triazolopyrimidines. It features a triazole ring fused to a pyrimidine ring, with a fluorine atom at the 5-position and an amino group at the 7-position. 5-fluoro-7aH-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine is of interest in medicinal chemistry due to its potential as a building block for the development of new drugs, particularly in the area of antiviral and anticancer therapies. Its unique structure allows for the exploration of various chemical modifications to optimize its biological activity and selectivity. The compound's synthesis and properties are subjects of ongoing research, with the aim of understanding its interactions with biological targets and its potential therapeutic applications.

7498-15-9

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7498-15-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7498-15-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,4,9 and 8 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 7498-15:
(6*7)+(5*4)+(4*9)+(3*8)+(2*1)+(1*5)=129
129 % 10 = 9
So 7498-15-9 is a valid CAS Registry Number.

7498-15-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-fluoro-2H-triazolo[4,5-d]pyrimidin-7-amine

1.2 Other means of identification

Product number -
Other names 2-fluoro-8-azaadenine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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More Details:7498-15-9 SDS

7498-15-9Upstream product

7498-15-9Downstream Products

7498-15-9Relevant academic research and scientific papers

Synthesis and Biological Evaluation of 2-Fluoro-8-azaadenosine and Related Compounds

Montgomery, John A.,Shortnacy, Anita T.,Secrist, John A.

, p. 1483 - 1489 (2007/10/02)

The synthesis of 2-fluoro-8-azaadenosine (6e) and 2-amino-8-azaadenosine (6d) is described.Condensation of 9H-2,6-bis(methylthio)-8-azapurine (4) with 2,3,5-tri-O-acetyl-D-ribofuranosyl chloride (5) produces a mixture of 6a (9-β-D-ribofuranosyl) and 7a (8-β-D-ribofuranosyl).Standard functional group manipulation, including a modified Schiemann reaction to introduce the fluorine, allows preparation of 6d and 6e from the major isomer 6a.By a similar series of reactions the minor component 7a was converted to 7d and 7e, with the ribose ring attached at N-8 of the 8-azapurine ring system.Structure proofs utilized UV and 1H and 13C NMR data.Compounds 6b-e,g and 7b-f were evaluated in the H.Ep.-2 cell culture screen, and compounds 6c-e and 7d were evaluated in the P388 mouse leukemia screen.Adenosine deaminase data are also presented for some compounds.

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