74982-79-9Relevant articles and documents
Synthesis of Polyfunctionally Substituted Pyridazines
Ghozlan, Said Ahmed Soliman,Mohamed, Mona Hassan,Fakhr, Yehia,Elnagdi, Mohamed Hilmy
, p. 293 - 296 (2007/10/02)
The pyridazines 3,4,5, and 7 were obtained by reaction of the hydrazone derivatives 2 with several reagents.By treatment of 5 with acetic acid/hydrochloric acid, the pyrazolopyridazine 6 was formed.The pyrido-pyridazine derivatives 8 and 9 were obtained by reaction of 2 and 3 with malononitrile and ethyl cyanoacetate, respectively, and the isoxazolo-pyridazines 11 by reaction of 3a,b with hydroxylamine hydrochloride in ethanolic sodium ethoxide solution.The intermediate 9 was separated by reaction of 3a,b with hydroxylamine hydrochloride in ethanolic sodium acetate solution.
Reactions with the Arylhydrazones of α-Cyanoketones: Utility of Arylhydrazonomesoxalonitriles for the Synthesis of Azoles and Azolines
Hafez, Ebtisam Abdel Aziz,Khalifa, Mohamed Ali Elsayed,Guda, Sayed Kamel Ahmed,Elnagdi, Mohamed Hilmy
, p. 485 - 489 (2007/10/02)
The arylhydrazonomesoxalonitriles derivatives 1 a-c were utilised for the synthesis of several new pyrimidine, pyridines, triazine and isoxazole derivatives.Compound 1a reacted with alkyl halides to yield the N-alkyl derivatives 12 a, b.The latter reacted