749900-28-5Relevant articles and documents
THE CHEMISTRY OF PHTALIDE-3-CARBOXYLIC ACID - I DECARBOXYLATION ON THE PRESENCE OF THE ALDEHYDES
Prager, Rolf H.,Schiesser, Carl H.
, p. 1517 - 1522 (1984)
The decarboxylation of phthalide-3-carboxylic acid (3-oxo-1,3-dihydroisobenzofuran-1-carboxylic acid) has been studied in the melt, in dimethylsulfoxide, and in the presence of aromatic aldehydes.The latter are efficiently trapped to produce mixtures of 3-arylidene-phthalides and 3-(arylhydroxymethyl)phthalides.Kinetic and other evidence supports the proposal that this reaction occurs in a tight cyclic transition state.