74991-91-6 Usage
Description
9-Methoxycanthin-6-one is a canthin-6-one alkaloid derived from the intact plant parts and callus cultures of Eurycoma longifolia, commonly known as Tongkat Ali. It is a naturally occurring compound with potential cytotoxic properties.
Used in Pharmaceutical Industry:
9-Methoxycanthin-6-one is used as a cytotoxic agent for its potential anticancer properties. It has been evaluated for its cytotoxic activity against a HT-1080 human fibrosarcoma cell line, indicating its potential use in cancer treatment and research.
Check Digit Verification of cas no
The CAS Registry Mumber 74991-91-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,9,9 and 1 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 74991-91:
(7*7)+(6*4)+(5*9)+(4*9)+(3*1)+(2*9)+(1*1)=176
176 % 10 = 6
So 74991-91-6 is a valid CAS Registry Number.
74991-91-6Relevant articles and documents
Two-step total syntheses of Canthin-6-one alkaloids: New one-pot sequential Pd-catalyzed Suzuki-Miyaura coupling and Cu-catalyzed amidation reaction
Gollner, Andreas,Koutentis, Panayiotis A.
supporting information; experimental part, p. 1352 - 1355 (2010/06/11)
Chemical Equation Presented Canthin-6-one (1) and nine analogues including the naturally occurring 9-methoxycanthin-6-one (2) and amaroridine (3) are prepared rapidly and in high yields via a convergent non-classical strategy that focuses on construction of the central ring B. The strategy relies on concomitant Pd-catalyzed Suzuki-Miyaura C-C coupling followed by a Cu-catalyzed C-N coupling that can be achieved either stepwise or in a new one-pot protocol starting from the appropriate 8-bromo-1,5-naphthyrldine.
