749916-89-0Relevant articles and documents
The successive substitution of halogens in 4-chloro-6-iodoquinoline by aryl groups in cross-coupling reactions with arylboronic acids
Tsvetkov, Alexey V.,Latyshev, Gennadij V.,Lukashev, Nikolai V.,Beletskaya, Irina P.
, p. 7267 - 7270 (2002)
The conditions for selective stepwise substitution of iodine and chlorine atoms in 4-chloro-6-iodoquinoline which allow the synthesis of the corresponding diarylquinolines with different aryl groups in the 4- and 6-positions, in a one-pot procedure, in hi
Successive replacement of halogen atoms in 4,6-dihaloquinolines in cross-coupling reactions with arylboronic acids catalyzed by palladium and nickel complexes
Beletskaya,Tsvetkov,Latyshev,Lukashev
, p. 1660 - 1667 (2007/10/03)
Conditions were found where in 6-halo-4-quinolines (halogen = iodine, bromine, or chlorine) the halogen atoms were replaced in succession by similar or different aryl groups in cross-coupling reactions with arylboric acids catalyzed by palladium and nickel complexes. Basing on successive Suzuki reaction a convenient procedure was developed for preparation of diarylquinolines that did not require isolation of the intermediate monoarylation product and afforded almost quantitative yields of diarylquinolines.
