749922-66-5Relevant academic research and scientific papers
A new route to optically pure highly functionalized tetrahydro-isoquinolines with a quaternary carbon stereocenter
Ka?uza, Zbigniew,Mostowicz, Danuta,Do?ega, Grzegorz,Wójcik, Robert
, p. 2321 - 2328 (2008/09/18)
A facile synthesis of highly substituted, optically pure tetrahydro-isoquinolines with a quaternary carbon stereocenter is described. Glycolic cleavage of 1,2-dihydroxy-hexahydro-pyrrolo-isoquinolines 1 affords a mixture of cyclic hemiacetals, which can b
