75037-46-6

Basic information

• Product Name: GELONIN FROM GELONIUM MULTIFLORUM
• Synonyms: GELONIN FROM GELONIUM MULTIFLORUM;gelonin
• CAS NO: 75037-46-6
• Molecular Weight: 0
• Mol File: 75037-46-6.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• CAS DataBase Reference: GELONIN FROM GELONIUM MULTIFLORUM(CAS DataBase Reference)
• NIST Chemistry Reference: GELONIN FROM GELONIUM MULTIFLORUM(75037-46-6)
• EPA Substance Registry System: GELONIN FROM GELONIUM MULTIFLORUM(75037-46-6)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22
• Safety Statements: 36
• Hazardous Substances Data: 75037-46-6(Hazardous Substances Data)

Usage

General Description

Gelonin is a type I ribosome-inactivating protein (RIP) derived from the seeds of the Gelonium multiflorum plant, also known as "wild ginger." It is a highly potent toxin that inhibits protein synthesis by disrupting the ribosomal machinery, leading to cell death. Gelonin has been studied extensively for its potential applications in targeted cancer therapy and immunotoxin development, due to its ability to selectively kill cancer cells. Additionally, gelonin has been investigated for its potential use as a biopesticide and in the treatment of autoimmune diseases, but its clinical use is limited by its immunogenicity and potential off-target effects. Despite these challenges, gelonin remains an important molecule for biotechnology research and potential therapeutic development.