750595-47-2Relevant academic research and scientific papers
Hexamethylenetetramine as a cheap and convenient alternative catalyst in the Baylis-Hillman reaction: Synthesis of aromatic compounds with anti-malarial activity
De Souza,Meireles, Bruno A.,Aguiar, Lucia C. S.,Vasconcellos
, p. 1595 - 1600 (2004)
Hexamethylenetetramine (7, HMT) is a cheap alternative catalyst in the Baylis-Hillman reaction between aromatic aldehydes and methyl acrylate or acrylonitrile. The use of 0.1 equiv or 1.0 equiv of HMT proved to be an efficient catalyst for the preparation
High selective leishmanicidal activity of 3-hydroxy-2-methylene-3-(4-bromophenyl)propanenitrile and analogous compounds
de Souza,Pereira,Muzitano,Falcao,Rossi-Bergmann,Filho,Vasconcellos
, p. 99 - 102 (2007/10/03)
Sixteen not new aromatic compounds were prepared by one-pot reaction i.e. through Baylis-Hillman reaction and were the first time evaluated against promastigote Leishmania amazonensis and infected mammalian cells. Most of the compounds were selectively mo
