7506-98-1

Basic information

• Product Name: diethyl [(2-chlorophenyl)(hydroxy)methyl]phosphonate
• Synonyms: .alpha.-Toluenephosphonic acid, o-chloro-.alpha.-hydroxy-, diethyl ester; Phosphonic acid, (O-chloro-alpha-hydroxybenzyl)-, diethyl ester
• CAS NO: 7506-98-1
• Molecular Formula: C₁₁H₁₆ClO₄P
• Molecular Weight: 278.6691
• Mol File: 7506-98-1.mol
• Article Data: 29

Chemical Properties

• Boiling Point: 387.6°C at 760 mmHg
• Flash Point: 188.2°C
• Density: 1.273g/cm³
• Vapor Pressure: 1.06E-06mmHg at 25°C
• Refractive Index: 1.519
• CAS DataBase Reference: diethyl [(2-chlorophenyl)(hydroxy)methyl]phosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl [(2-chlorophenyl)(hydroxy)methyl]phosphonate(7506-98-1)
• EPA Substance Registry System: diethyl [(2-chlorophenyl)(hydroxy)methyl]phosphonate(7506-98-1)

Safety Data

• Hazardous Substances Data: 7506-98-1(Hazardous Substances Data)

Upstream product

• 89-98-5 2-chloro-benzaldehyde 
• 122-52-1 triethyl phosphite 
• 762-04-9 Diethyl phosphonate 
• 762-04-9 phosphonic acid diethyl ester 

Downstream Products

• 212071-38-0 C₁₉H₃₅ClN₂O₄P₂ 
• 18442-44-9 diethyl α-trimethylsilyloxy-2-chlorobenzylphosphonate 
• 1614827-43-8 O,O-diethyl 1-((4,6-dichloropyrimidin-2-yl)carbamyloxy)-1-(2-chlorophenyl)methylphosphonate 
• 1024598-68-2 1-(2-chlorophenyl)-1-hydroxymethylphosphonic acid 
• 16656-42-1 diethyl ortho-chlorobenzoylphosphonate 

Relevant articles and documents

Method for synthesizing aromatic ring-containing alpha-hydroxyphosphonate through copper catalysis

The invention relates to a method for synthesizing aromatic ring-containing alpha-hydroxyphosphonate through copper catalysis. The method comprises the following steps: dissolving diethyl phosphite and aromatic aldehyde in an organic solvent, adding a cop

CeCl3?7H2O-catalysed hydrophosphonylation of aldehydes and ketones: An expeditious route to α-hydroxyphosphonates under solvent-free conditions

A cerium(III) chloride-catalysed expeditious synthesis of α-hydroxyphosphonates via a modified Abramov synthetic protocol has been developed. The scope of the current protocol is broad, with a range of aromatic, α,β-unsaturated and heterocyclic aldehydes

Bi(NO3)3.5H2O catalyzed phosphonylation of aldehydes: An efficient route to α-hydroxyphosphonates

The Bi(NO3)3.5H2O mediated synthesis of α-hydroxyphosphonates via phosphonylation of aldehydes is reported herein. Both conventional and microwave technology was efficiently applied to range of aromatic, heteroaromatic, α,