750644-74-7

Upstream product

• 920-46-7 Methacryloyl chloride 
• 750644-73-6 (1S,4R,7R)-7-Benzyl-4,7-dimethyl-2-aza-bicyclo[2.2.1]heptan-3-one 
• 750644-70-3 (1R,2S,3S)-2-Benzyl-1,2-dimethyl-cyclopentane-1,3-dicarboxylic acid dimethyl ester 
• 750644-71-4 (1R,2S,3S)-2-Benzyl-1,2-dimethyl-cyclopentane-1,3-dicarboxylic acid 1-methyl ester 
• 750644-72-5 (1R,2R,3S)-2-Benzyl-3-methoxycarbonylamino-1,2-dimethyl-cyclopentanecarboxylic acid methyl ester 

Relevant academic research and scientific papers

Toward the development of a general chiral auxiliary 10: Enhancement of diastereoselectivity in Diels-Alder reactions of imides derived from a new bicyclic lactam chiral controller molecule

Based upon X-ray structural information derived from a series of camphor-derived bicyclic lactam chiral controller molecules, a new auxiliary has been designed which affords superior diastereoselectivity (>95:5) in Diels-Alder reactions with common dienes but of opposite π-facial selectivity than previously observed with this class of chiral controller. A rationale for the selectivity based on subtle structural changes in the chiral controller is discussed.