75072-73-0

Upstream product

• 36185-09-8 1-phenylhex-5-yn-3-ol 
• 104-53-0 3-phenyl-propionaldehyde 
• 106-96-7 propargyl bromide 
• 61157-31-1 3-phenylpropionyltrimethylsilane 
• 75072-61-6 6-methoxy-1-phenyl-3-trimethylsilyl-4-hexyn-3-ol 

Downstream Products

• 1185447-02-2 C₂₄H₂₄O₂ 
• 1185446-35-8 C₂₅H₂₂O₃ 
• 1185446-77-8 C₁₄H₁₄O₃ 
• 1256348-13-6 C₂₁H₂₀S 
• 1256348-05-6 C₁₅H₁₆O 
• 1432479-36-1 C₁₈H₂₀O₄ 
• 1432479-50-9 C₃₀H₃₂O₅ 
• 1454271-74-9 (E)-5-fluoro-1-phenylhex-4-en-3-one 
• 1454271-93-2 (Z)-5-fluoro-1-phenylhex-4-en-3-one 
• 1590402-80-4 ethyl 2-methyl-1-(3-phenylpropanoyl)indolizine-3-carboxylate 
• 1590402-58-6 1-(3-benzoyl-2-methylindolizin-1-yl)-3-phenylpropan-1-one 

Relevant academic research and scientific papers

Synthesis of Acyl Alkenylindium Reagents and Their Application in the Synthesis of (Z)-α,β-Unsaturated Ketones via Palladium-Catalyzed Cross-Coupling Reaction

A synthetic method for the preparation of acyl alkenylindium reagents was developed involving the hydroindation reaction of allenyl ketones with indium and indium chloride in methanol under mild conditions. Their synthetic applications were demonstrated from Pd-catalyzed cross-coupling reactions with aryl bromides and iodides and alkenyl and aryl triflates for the synthesis of (Z)-α,β-unsaturated ketones.

Mechanochemically Induced Dehydrogenation Coupling and [3+2] Cycloaddition of Indolizines with Allenes Using Piezoelectric Materials

A wide range of indolizines with allenes proceeded smoothly under mechanochemically induced conditions via a [3+2] annulation process, affording various substituted pyrrolo[2,1,5-cd]indolizines in good yields. The reaction efficiency was greatly improved

Synthesis of vinylic sulfones in aqueous media

A green method for the sulfination of allenic carbonyl compounds to access a wide variety of vinylic sulfones is developed. This reaction works in aqueous media under very mild conditions. This reaction is atom economic. A wide variety of vinylic sulfones could be obtained in moderate to excellent yields with wide functional group tolerance. The efficiency of this method is demonstrated in some reactions where the desired products can be isolated by filtration.

Revisiting the Addition of in-situ Nucleophiles to Allenic Ketones: An Entry Towards Synthesis of Benzodioxins

The manuscript delineates a revisit towards regioselective addition of in situ generated negative nucleophiles to allenic ketones in the presence of a base. A wide variety of allenic ketones as well as nucleophiles are viable in this transformation. A dir

Sustainable and selective synthesis of 3,4-dihydroquinolizin-2-one and quinolizin-2-one derivatives via the reactions of penta-3,4-dien-2-ones

In this paper, a novel and green methodology for the synthesis of 3,4-dihydroquinolizin-2-one derivatives via the tandem reactions of penta-3,4-dien-2-ones with pyridine, quinoline, or isoquinoline at rt in aqueous ethanol was developed. Notably, the reac

InI3- or ZnI2-catalyzed reaction of hydroxylated 1,5-allenynes with thiols: A new access to 3,5-disubstituted toluene derivatives

Transition-metal-activated alkynes or allenes can accept nucleophilic attack and undergo direct addition of the nucleophiles to the unsaturated bonds or trigger subsequent rearrangement reactions. This chemistry has witnessed increasing development in recent years. In this report, we have focused on the metal-catalyzed reactions of a variety of substituted propargyl allenic alcohols and thiophenols using indiumACHTUNGTRENUNG(III) and zinc(II) catalysts, which can activate both the alcohol and alkyne. In this reaction, thio groups play the role of a nucleophile and trigger subsequent rearrangements to give benzene derivatives. The products can be further transformed into various 1,3,5-trisubstituted aromatic compounds by nickel-catalyzed coupling reactions through the cleavage of the C-S bonds.

Double deprotonation of acetylenic oxiranes: Synthesis of allenic ketones through dilithio ynenolates

(Chemical Equation Presented) The double deprotonation of acetylenic oxiranes gives allenic ketones through the 1,2-H or 1,2-Ar shift on the transient oxiranyl dianion intermediates. The resulting dilithium ynenolates give allenic ketones upon hydrolysis

SPECIFIC GENERATION OF LITHIATED 3-TRIMETHYLSILOXY-1,2-PROPADIENE DERIVATIVES FROM 1-(TRIMETHYLSILYL)PROPARGYL ALCOHOLS.

1-(Trimethylsilyl)propargyl alcohols have been prepared by treating acyltrimethylsilanes with magnesium acetylides, and their base-induced reactions involving rearrangement of silyl group have been examined. Treatment of the alcohol with an equimolar amou

BASE-INDUCED REARRANGEMENT OF 1-TRIMETHYLSILYLPROPARGYL ALCOHOL. GENERATION OF LITHIATED TRIMETHYLSILOXYALLENES AND THEIR REACTIONS

Under the effect of butyllithium, 1-trimethylsilylpropagyl alcohol undergoes rearrangement to afford the corresponding trimethylsiloxyallene or its lithiated one, which can be used for the preparation of α,β-unsaturated ketone derivatives.