75073-53-9Relevant academic research and scientific papers
Palladium-catalyzed direct arylation of selenophene
Rampon, Daniel S.,Wessjohann, Ludger A.,Schneider, Paulo H.
, p. 5987 - 5992 (2014/07/21)
An efficient and convenient method was developed for the regioselective formation of 2-aryl- or 2,5-diarylselenophenes via a palladium-catalyzed direct arylation. This protocol is suitable for a wide range of aryl halides containing different functional groups. The 2-arylated substrates can undergo an additional regioselective direct arylation event furnishing symmetrical or unsymmetrical 2,5-diaryl selenophenes in good yield. Competition experiments and the role of the acid additive are in agreement with a concerted metalation deprotonation (CMD) pathway.
