7508-77-2Relevant academic research and scientific papers
Direct arylation under catalysis of an oxime-derived palladacycle: Search for a phosphane-free method
Zhang, Guofu,Zhao, Xiaobao,Yan, Yunbing,Ding, Chengrong
, p. 669 - 672 (2012/03/27)
A phosphane-free method for the direct arylation of benzothiazole by employing oxime-derived palladacycle 1 as a catalyst was developed. The new catalyst system can be used for 2-arylations by using aryl bromides and iodides. In addition, this method is especially suitable for the intramolecular direct coupling of bromo-and iodoamides, as well aschloroamides, to achieve a rapid synthesis of benzo[c]phenanthridine alkaloids. Direct arylation reactions under catalysis of an oxime-derived palladacycle were investigated. This phosphane-free method is applicable for the 2-arylation of benzothiazole and is especially suitable for the intramolecular direct coupling of bromo-and iodoamides, as well as chloroamides, to achieve rapid synthesis of benzo[c]phenanthridine alkaloids. Copyright
Substituted 2-phenyl-4-quinolone-3-carboxylic acid compounds and their use as antitumor agents
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Page/Page column 7, (2008/06/13)
Substituted 2-phenyl-4-quinolone-3-carboxylic acid derivatives and their salts were synthesized. The results of preliminary screening revealed that these compounds are potent in killing solid tumor cancers.
