751-58-6Relevant academic research and scientific papers
Generation of cycloheptynes and cyclooctynes via a sulfoxide-magnesium exchange reaction of readily synthesized 2-sulfinylcycloalkenyl triflates
Yoshida, Suguru,Karaki, Fumika,Uchida, Keisuke,Hosoya, Takamitsu
, p. 8745 - 8748 (2015/05/20)
Cycloheptynes and cyclooctynes were efficiently generated via a sulfoxide-magnesium exchange reaction of readily synthesized 2-sulfinylcycloalkenyl triflates. Cycloadditions between various ynophiles and the cycloalkynes generated by this method proceeded
Bi-3H-diazirin-3-yls as precursors of highly strained cycloalkynes
Al-Omari, Mohammad,Banert, Klaus,Hagedorn, Manfred
, p. 309 - 311 (2007/10/03)
(Chemical Equation Presented) No reagents and very mild conditions are required for the transformation of isolable precursors 3 into highly strained cycloalkynes 4 (cycloheptyne, cyclohexyne, norbornyne), which can be trapped by cycloaddition reactions.
A spontaneous fragmentation: From the Criegee zwitterion to coarctate Mobius aromaticity
Berger, Christian,Bresler, Christian,Dilger, Ulrich,Geuenich, Daniel,Herges, Rainer,Roettele, Herbert,Schroeder, Gerhard
, p. 1850 - 1853 (2007/10/03)
The extremely fast fragmentation of the spiroozonides prepared from formaldehyde O-oxide and three-membered ring ketones proceeds via the coarctate transition state 1. The ozonides decompose at temperatures as low as -90°C to form carbon dioxide, alkene/alkyne, and formaldehyde (the topology of the structure of 1 is depicted on the right). The mechanism is in accordance with the rules for the stereochemical course of coarctate reactions.
