75102-75-9Relevant articles and documents
Synthesis and Investigation of the Abiotic Formation of Pyonitrins A-D
Aniebok, Victor,Lee, Hsiau-Wei,Macmillan, John B.,Shingare, Rahul D.
, (2020/02/22)
Pyonitrins A-D are recently isolated natural products from the insect-associated Pseudomonas protegens strain, which were isolated from complex fractions that exhibited antifungal activity via an in vivo murine candidiasis assay. Genomic studies of Pseudomonas protegens suggested that pyonitrins A-D are formed via a spontaneous nonenzymatic reaction between biosynthetic intermediates of two well-known natural products pyochelin and pyrrolnitrin. Herein we have accomplished the first biomimetic total synthesis of pyonitrins A-D in three steps and studied the nonenzymatic formation of the pyonitrins using 15N NMR spectroscopy.
Synthesis of pyrrolnitrin and related halogenated phenylpyrroles
Morrison, Matthew D.,Hanthorn, Jason J.,Pratt, Derek A.
supporting information; experimental part, p. 1051 - 1054 (2009/07/18)
A general approach to halogenated arylpyrroles, including the antifungal natural product pyrrolnitrin, is described using newly synthesized halogenated pyrroles and 2,6-disubstituted nitrobenzenes or 2,6-disubstituted anilines.
Bildung von Pyrrolnitrin und 3-(2-Amino-3-chlorphenyl)pyrrol aus 7-Chlortryptophan
Pee, Karl-Heinz van,Salcher, Olga,Lingens, Franz
, p. 855 - 856 (2007/10/02)
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