75115-03-6

Basic information

• Product Name: 4-Bromo-5-methyl-3,5-diphenyl-4,5-dihydro-isoxazole
• Synonyms: 4-Bromo-5-methyl-3,5-diphenyl-4,5-dihydro-isoxazole
• CAS NO: 75115-03-6
• Molecular Weight: 316.197
• Mol File: 75115-03-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Bromo-5-methyl-3,5-diphenyl-4,5-dihydro-isoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Bromo-5-methyl-3,5-diphenyl-4,5-dihydro-isoxazole(75115-03-6)
• EPA Substance Registry System: 4-Bromo-5-methyl-3,5-diphenyl-4,5-dihydro-isoxazole(75115-03-6)

Safety Data

• Hazardous Substances Data: 75115-03-6(Hazardous Substances Data)

Upstream product

• 5455-12-9 1,3-diphenyl-but-2-en-1-one oxime 
• 1089717-81-6 oxime of trans-dypnone 

Downstream Products

• 37928-17-9 5-methyl-3,4-diphenyl isoxazole 

Relevant articles and documents

Halogenation of Vinyl Ketoximes. Synthesis of Isoxazoles and Preparation and Silver Ion-Promoted Reactions of 4-Halo-2-isoxazolines

Reaction of several α,β-unsaturated ketoximes with N-bromosuccinimide (NBS) gave isoxazoles, but yields were lower and the reaction less general than a similar transformation using iodine under basic conditions.With β,β-disubstituted oximes, 4-halo-5,5-disubstituted-2-isoxazolines were obtained using NBS, iodine, or N-chlorosuccinimide.Treatment of the 4-bromoisoxazolines with silver acetate or silver nitrate caused either elimination with rearrangement to give isoxazoles or substitution at C-4, depending upon the nature of the substituents at C-5.