75140-49-7

Upstream product

• 72955-39-6 methyl 2-cyano-3-(2-methoxyphenyl)acrylate 
• 135-02-4 ortho-anisaldehyde 

Downstream Products

• 115787-71-8 2,6-diamino-3,5-dihydro-7-<(2-methoxyphenyl)methyl>-4H-pyrrolo<3,2-d>pyrimidin-4-one hydrochloride 
• 140676-88-6 2-amino-α-<(2-methoxyphenyl)methyl>-1,6-dihydro-5-nitro-6-oxo-4-pyrimidineacetonitrile 
• 140676-89-7 2-(2,5-Diamino-6-oxo-1,6-dihydro-pyrimidin-4-yl)-3-(2-methoxy-phenyl)-propionitrile 
• 140676-84-2 2-amino-α-cyano-1,6-dihydro-5-nitro-6-oxo-α-<(2-methoxyphenyl)methyl>-4-pyrimidineacetic acid methyl ester 

Relevant academic research and scientific papers

Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-th

Purine nucleoside phosphorylase (PNP) is a purine-metabolizing enzyme in the purine cascade and has been a target for drug design for sometime. A series of potent human PNP inhibitors, pyrrolo[3,2-d]pyrimidines (9- deazaguanines), has been synthesized and