75143-78-1

Basic information

• Product Name: 5-[(E)-2-(2,4-Dichloro-phenyl)-vinyl]-3-methyl-4-nitro-isoxazole
• Synonyms: 5-[(E)-2-(2,4-Dichloro-phenyl)-vinyl]-3-methyl-4-nitro-isoxazole
• CAS NO: 75143-78-1
• Molecular Weight: 299.113
• Mol File: 75143-78-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-[(E)-2-(2,4-Dichloro-phenyl)-vinyl]-3-methyl-4-nitro-isoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[(E)-2-(2,4-Dichloro-phenyl)-vinyl]-3-methyl-4-nitro-isoxazole(75143-78-1)
• EPA Substance Registry System: 5-[(E)-2-(2,4-Dichloro-phenyl)-vinyl]-3-methyl-4-nitro-isoxazole(75143-78-1)

Safety Data

• Hazardous Substances Data: 75143-78-1(Hazardous Substances Data)

Upstream product

• 1123-49-5 3,5-dimethyl-4-nitroisoxazole 
• 874-42-0 2,4-dichlorobenzaldeyhde 

Downstream Products

• 1205553-74-7 (S)-5-(2-(2,4-dichlorophenyl)-3-nitropropyl)-3-methyl-4-nitroisoxazole 
• 132869-26-2 3-(2,4-dichlorophenyl)-4-(3-methyl-4-nitroisoxazol-5-yl)butanoic acid 
• 132869-31-9 5,6,7,8-tetrahydro-7-(2,4-dichlorophenyl)-3-methyisoxazolo<4,5-b>azepin-5(4H)-one 
• 42829-25-4 2,4-Bis-(2,4-dichloro-phenyl)-cyclobutane-1,3-dicarboxylic acid dimethyl ester 
• 42829-24-3 2,2',4,4'-tetrachloro-α-truxilic acid 
• 132894-39-4 ethyl 2-carbethoxy-3-(2,4-dichlorophenyl)-4-(3-methyl-4-nitroisoxazol-5-yl)butyrate 
• 108175-95-7 C₂₄H₁₆Cl₄N₄O₆ 
• 1201-99-6 trans-2,4-dichlorocinnamic acid 

Relevant articles and documents

Catalytic asymmetric conjugate addition of nitroalkanes to 4-nitro5-styrylisoxazoles

(Chemical equation presented) Nitro versus nitro: 4-Nitro-5- styrylisoxazoles were used as masked α,β-unsaturated carboxylic acids in the titled catalytic asymmetric transformation. The 4-nitroisoxazole core acts as an activator of the conjugated alkene and a latent carboxylate functionality. The reaction proceeded with 5 mol% of a readily prepared phasetransfer catalyst at room temperature with remarkable diastereo- and enantioselectivity (see scheme).